Take Exit 176 For Us-501 Bus S Toward N Duke St/Downtown: This Exit Will Lead You Toward The Downtown Area Of Durham. Merge Onto Us-501 Bus S/N Duke St: Continue On N Duke Street Heading South. Turn Left Onto W Trinity Ave: After Approximately 0.5 Miles On N Duke Street, Turn Left Onto W Trinity Avenue. Turn Right Onto North St: Drive About 0.2 Miles On W Trinity Avenue, Then Turn Right Onto North Street. Arrive At 1008 North St: The Destination Will Be On Your Left After A Short Distance.